pomegrnata oil for your psoriasis

pomegrnata oil 

The pomegranate is native to India, Egypt and regions of the Middle East.  Each  pomegranate  contains  hundreds  of  seeds  that  yield  a highly  nourishing  cosmeceutical  oil.  Natural  Sourcing  provides superior  quality  pomegranate  seed  oil  with  a  high  punicic  acid (CLA) content of about 84%. It is carefully processed and packaged to maintain  the  purity,  freshness  and  beneficial  properties  of  this exceptional oil.

 

Pomegranate  seed  oil  possesses  powerful  antioxidant  properties , so it can interfer inflammatory product like PG (prostaglandin) , nuclear factor-kappaB (NFκB) and toxic material formed  . remarkable ability  to nourish, moisturize and  repair  the epidermis and  improve  skin  elasticity.  It has a unique healing property of Pomegranate seed oil .

It's used for Mature, ageing skin, Dry, cracked skin , Eczema, psoriasis and other skin conditions, Sun exposed or damaged skin

Pomegranate oil will be effective if you add to your baths for relieving psoriasis . 

Water Therapy

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Water therapy is the combination of sea salts and water and is the basis of many powerful therapeutic treatments. There are numerous types of Water Therapy administered at spas, ayurvedic & holistic centers, and health clinics around the world. Sports therapy clinics use Hydrotherapy Baths to help patients recover from joint and muscle injuries. Dermatologists are recommending Bokek Dead Sea Salt baths for patients with psoriasis, eczema and other dry skin conditions. Estheticians emphasize the cleansing properties of a sea salt bath to clean pores and to detoxify the body. Cancer patients use water therapy to help deal with radiation treatments. There are even Water Therapies & therapeutic bath salts you can use on a daily or weekly basis in your own home.

Hippocrates, the Father of Medicine, discovered the therapeutic qualities of seawater by noticing the healing affects it had on the injured hands of fishermen. The seawater not only restricted infection risks, but patients who followed treatments involving the use of seawater found that it also promoted pain relief. It is now known that sea salt therapy is an effective treatment that assists in the rejuvenation of the cells and also induces a healthy exchange of minerals and toxins between the blood and the water.

Types of Water Therapies

Balneotherapy - a range of treatments with warm mineral salt water, from bathing or underwater massage jets to plain drinking. Alkaline water helps stimulate the secretion of bile, while hypnotic water has diuretic effects and is often used for treating kidney stones.

Heliotherapy - use of the sun’s creative properties. Despite recent awareness of skin cancers, sun remains an excellent source of energy, boosts immunity and stabilizes mood when used appropriately. Skin treatments combine this with sea salt baths but should only be used together under the supervision of a doctor.

Phytotherapy - treatments with wild-growing herbs, plants, flowers or leaves. Used in salt baths, oils or infusions, their effect can be superior to pharmacological treatments for some medical conditions. Try making your own bath salts by combining these ingredients with sea salts.

Thalassotherapy - therapeutic baths using warm seawater. The application of seawater (which is very similar to the body’s own internal fluids) allows magnesium and potassium to be drawn into the blood stream while toxins are actively eliminated.

Climatotherapy of Psoriasis at  Safaga Red Sea - Climatotherapy has become a well-established modality for the treatment of psoriasis. It involves various regimens of seawater bathing and sunlight exposure, combined with application of emollients, rest and relaxation over several weeks

Safaga at the Red Sea was found an ideal area for climatotherapy of psoriasis. Many natural factors and present there: plentiful sunshine due to cloudless sky prevailing at least 350 days a year, warm, clear, non-polluted or dusty weather. These elements constitute the main components of the natural therapy of the disease at this area.

A natural selective ultraviolet phototherapy along with bathing in the sea was utilized in the management of psoriasis at Safaga – Red Sea. In 80 patients with psoriasis, 90% achieved complete clearing or excellent improvement. The results compare favorable with other therapeutic regiments used in the treatment of psoriasis. Since systemic medications are avoided, the advantage of Safaga – Climatotherapy is that the treatment is natural, pleasant and without the serious side effects sometimes associated with other methods.

Dead Sea Psoriasis Treatments - The Dead Sea area has become a major center for health research and psoriasis treatment for several reasons. The mineral content of the waters, the very low content of pollens and other allergens in the atmosphere, the reduced ultraviolet component of solar radiation, and the higher atmospheric pressure at this great depth each have specific health effects. For example persons suffering reduced respiratory function from diseases such as cystic fibrosis, seem to benefit from the increased atmospheric pressure.

Sunlight at the Dead Sea is high in therapeutic UVA rays and low in burning UVB, so extended exposure is safe and low-risk. The filtering effect comes from a thick atmosphere: the Dead Sea is about 1,200 feet below sea level and the ozone layer above it is minimally depleted. The Dead Sea is the only place on Earth where you can sunbathe for extended periods with little or no sunburn because harmful ultraviolet rays are filtered through three natural layers: an extra atmospheric layer, an evaporation layer that exists above the Dead Sea, and a rather thick ozone layer.

Ichthyotherapy ( therapy with theso-called‘ Doctorfish of Kangal’, Garrarufa ) has been shown to be effective inpatients with psoriasis in the Kangal hot springsin Turkey. This treatment was first mentionedin The Lancetin 1989 but the details of the treatment were published only recently by Ozcelik etal. According to the authors two Different types of fish live in the pools of the Kangalhot spring: Cyprinionm acrostomus and Garrarufa. Both fish are members of the carpandminnow family (Cyprinidae). Garrarufa is regarded as the main therapeutic. Garrarufa is normally a bottom dweller ,where it adheres by suction to rocks with its ventral crescent shaped mouth to feed on phyto and zooplankton However , in the hot pools of Kangal , where phyto - and zooplankton are scarce , these fish feed on the skin scales of bathers, reportedly reducing illnesses such as psoriasis and atopic dermatitis .Whether this remarkable treatment is also effective outside of the Kangal hot spring in Turkey is unknown . Since there have been many unscientific and misleading names for this kind of therapy , we suggest the term ‘ichthyotherapy’ , in accordance with other so called biotherapy concepts such as maggot therapy (use of sterile fly larvae), hirudo therapy(use of leeches) and apitherapy ( use of bee venom).

Herbal Medicine For Psoriasis

There are many herbal formulations are used for treatment psoriasis , But in this paper we will discuss drugs with scientific evidence from publications , books and scientific sites .

New drug developed by Egyptian Dr/agharied consists of aloe vera gel_, propolis ( Aloreed ).

Aloe is one of the known herbs in treatment psoriasis . Aloe vera gel is the mucilaginous gel produced from the centre (the parenchyma) of the plant leaf. The gel portion of the plant is prepared by peeling the outer portion of the skin and the pericarp away. It is the preparation which is called ‘pure Aloe vera gel’ in commerce. the condensed juice of Aloe barbadensis leaves. The gel contains enzymes, minerals, vitamins, and saponins and has anti-inflammatory and antibacterial effects. It is commonly added to cosmetics for its moisturizing, regenerative, elasticity-promoting properties, analgesic, antiallergic, antipruritic, wound healing and anti-inflammatory components such as amino acids .

propolis (bee glue) is a sticky dark-colored material that honeybees collect from living plants, mix it with wax and use it in the construction an adaptation of their nests, mainly to fill out cracks in the bee hive. It has been used in folk medicine since ancient times and is now known to be a natural medicine and it varies in some of its components according to source . Whereas bud exudates of different poplar species and clones are frequently similar in qualitative composition, they may differ in their quantitative composition. These differences are reflected in the composition of propolis into which the bud exudate is incorporated .

Raw propolis is composed of approximately 50% resin (polyphenolic fraction), 30% wax, 10% essential oils, 5% pollen and 5% various organic and inorganic compounds  Chemical composition of propolis is very complex. More than 200 compounds have been identified . Its biological activity depends on compounds from the polyphenolic fraction, mainly flavonoids, followed by aromatic acids, phenolic acid esters, triterpenes, lignans, etc. It is included in dermatological preparations used for tissue regeneration and wound healing, for the treatment of psoriasis, morphea, herpes simplex and herpes genitalis and anal pruritus, and it is also a component of antidermatophyte preparations, also it has antibacterial, antifungal, antitumoral, antioxidative, imunomodulatory and other beneficial activities .

Theraflax (Department of Dermatology and Venereology, Medical Faculty-sofia,Bulgaria) , which consists of alpha-linolenic acid, linoleic acid, oleic acid, gamma-linolenic acid, palmitic acid and other fatty acids .

Evening primrose (Oenothera biennis) Gamolenic acid and its metabolite dihomogamma-linolenic acid (DGLA) are precursors of both the inflammatory prostaglandin E2 (PGE2) series via arachidonic acid (AA), and of the less inflammatory prostaglandin E1 (PGE1) series. Actions attributed to PGE1 include anti-inflammatory, immunoregulatory and vasodilatory properties, inhibition of platelet aggregation and cholesterol biosynthesis, hypotension and elevation of cyclic AMP (inhibits phospholipase A2 ).

Dietary supplementation with gamolenic acid has been noted to have a favourable effect on the DGLA:AA ratio. Although an increase in arachidonic acid concentrations is also seen, this is much smaller and less consistent compared with the increase seen for DGLA.Contributory factors to this negative effect on arachidonic acid are PGE1 and 15-hydroxy-DGLA. The latter inhibits conversion of arachidonic acid to inflammatory lipoxygenase metabolites including leukotrienes, whilst PGE1 inhibits the enzyme phospholipase A2 which is required for the mobilisation of arachidonic acid from phospholipid membrane stores . Pregnant women should not use evening primrose oil.

Also these drugs as well as linseed (Linum usitatissimum) oil or flax seed oil can modify the metabolic changes associated with psoriasis , as a result of increased percent of saturated fatty acids in blood samples in comparison to the levels of poly un saturated  fatty acids (EFA)-linoleic and arachidonic, wich play an important role as structral compounds of membrane cell phospholipids.

Liqourice (Glycyrrhiza glabra) , fenugreek (Trigonella foenum-graecum) and sarsaparilla contain saponins that has anti-inflammatory effect and cortisone like effect as well as flavenoids that found in fenugreek and liqourice .

Ammi majus and angelica (Dong Quay ) contain psoralen ( furano coumarin ) it’s a planner compound can interact with DNA molecules: it was reported that interstrand cross links are formed in native DNA by irradiation with 360 nm light in the presence of psoralen ,and suggested that the cross-link may result from the reaction of an excited psoralen molecule with pyrimidine bases in opposite strands of the DNA duplex. 5-lipoxygenase (5-LO) inhibition with angelica that produce leukotriene B4 which contribute with inflammatory reactions .  

Chamomile (Matricaria recutita). The chamomile flowers have a long therapeutic tradition in treating gastrointestinal ailments. The rationale for its use in psoriasis is three-fold. First, chamazulene, a by-product of the non-volatile oil extract, matricin, has anti-inflammatory activity through the inhibition of lipoxygenase and, as a result, leukotriene B4 (LTB4) formation. There is evidence supporting the role of increased LTB4 formation in psoriatic plaques; therefore, inhibition results in disease improvement (Aggag & Yousef, 1972). Second, chamomile oil has antimicrobial activity against skin pathogens, Staphylococcus and Candida (Leung, Walsh, Giorno, & Norris, 1993). Lastly, the flavonoids, quercetin and apigenin, are also active compounds of the flower. Quercetin, a potent inhibitor of lipoxygenase, and to a lesser degree, cyclooxygenase, is readily absorbed through the skin (Brown & Dattner, 1998; Kim, Mani, Iversen, & Ziboh, 1998). As of yet, there are no clinical trials assessing the efficacy and adverse side effect profiles of chamomile reported in the treatment of psoriasis. Contact dermatitis (delayed type hypersensitivity) and systematized allergic response, however, have been reported (Gruenwald, 2004; Paulsen, 2002).

Wintergreen/Boxberry (Gaultheria pro cumbens). Wintergreen is a plant native to the Eastern United States, and historically was used by Native Americans as an analgesic. The methyl salicylate constituent is responsible for its anti-inflammatory properties. Although used topically for psoriasis, wintergreen can cause systemic effects. Brubacher and Hoffman (1996) reviewed 20 cases of systemic salicylate toxicity (tinnitus, vomiting, tachypnea, and acid-base disturbances) from using topical creams (Bell & Duggin, 2002). Pa tients at greatest risk are those using aspirin or a prescribed salicylic acid compound in conjunction with a salicylate herbal (for example, wintergreen, aloe vera, or red clover). Additionally, oil of wintergreen can increase prothrombin time and international normalized ratio of clotting, creating problems for pa tients on warfarin (Chan, 1996). There are no investigations on its effectiveness in psoriasis .

Milk thistle (Silybum marianum). The medicinal utility of milk thistle flower seeds dates back to Pliny the Elder, a Roman naturalist, who described its use in treating liver disease. A hepatoprotective effect is im parted through the flavonoid active ingredient, silymarin. Sily marin alters hepatocyte cell membranes, thereby blocking the toxin-binding sites. Additionally, glutathione, which aids in the detoxification function of the liver, is increased by silymarin. Double-blind, placebo-controlled clinical trials evaluating the efficacy of silymarin on liver function, however, have shown conflicting results. In a study of patients with liver cirrhosis, no difference in survival was found with silymarin compared to placebo (Pares et al., 1998). Another study showed no improvement in cirrhotic liver function after 2 years of treatment; however, benefit was noted in portal hypertension (Ferenci et al., 1989). On the other hand, a significant decrease in liver enzymes was seen with 1 month of silymarin treatment in a group of patients with alcohol-induced liver disease (Salmi & Sarna, 1982). An insignificant de crease in total and conjugated bilirubin was found in the same study.

Numerous changes have been detected in the liver of patients with psoriasis, including steatosis, periportal inflammation, fibrosis, necrosis, and cirrhosis (Pietrzak, Lecewicz-Torun, & Kadziela-Wypyska, 1998). A multifactorial etiology of liver disease in patients with psoriasis has been discussed and includes changes due to alcohol use, nutritional factors, anti-psoriatic medications, and a direct effect of the psoriasis itself. A single case report of clearance of psoriatic arthritis following a portal shunt procedure for primary biliary cirrhosis supports a link (D'Amico, Palazzi, & Capani, 1999). The value of silymarin in the treatment of psoriasis may be due to its ability to improve endotoxin removal by the liver, inhibit cAMP phosphodiesterase, and inhibit leukotriene synthesis. Abnormally high levels of cAMP and leukotrienes have been observed in patients with psoriasis and normalization of these levels may improve the condition (Thorne Research, Inc., 1999). While not proven to directly benefit psoriasis, milk thistle may be of therapeutic value as a hepatoprotective adjunct therapy in patients on hepatotoxic medications.

Cayenne Chilli Pepper, Hot Pepper, Paprika, Red Pepper, Tabasco Pepper (Capsicum annuum, Capsicum frutescens). Cayenne, its chief component being capsaicin, is one of the herbal medicines with documented effectiveness in the English medical literature. One hypothesis on the pathogenesis of psoriasis suggests a neurogenic inflammatory etiology mediated through substance-P (SP). SP activates inflammatory cells and ultimately perpetuates vasodilatation, angiogenesis, and kerat inocyte hyperproliferation (Farber, Nickoloff, Recht, & Fraki, 1986). In accordance, psoriatic lesions are known to be more densely innervated with higher SP content than control or uninvolved psoriatic skin (Naukkarinen, Nickoloff, & Farber, 1989). Capsaicin stimulates the re lease of SP by binding to the vanilloid receptor on slow-conducting, unmyelinated type C neurons and ultimately leads to its depletion.